Studying Cancer Therapy Resistance Mechanisms in Humans and Preclinical Models

We use well annotated clinical databases paired with prospectively collected patient tumor banks and state of the art sequencing technologies to perform high quality translational research in solid tumors. Our tumor bank includes longitudinal samples collected before and during radiation and chemotherapy, which allows us to ask important questions about how cancer therapies are impacting tumor cells and the tumor microenvironment.  We take these observations, derived directly from patient data, to the bench to conceptualize, optimize and test novel drug and radiotherapy combinations, which are then moved forward in the context of investigator-initiated clinical trials.

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WE’RE HIRING!

Schwarz lab is growing. We have several positions open including senior scientist/lab manager, post doc/staff scientist and senior technician. We are actively recruiting graduate students (PhD and MSTP) and are open for rotations this fall and spring. We are a highly collaborative and fun group studying pancreas and ovarian cancer in addition to HPV related cancers. Please email jschwarz@wustl.edu for details.

Stanley receives RSNA grant

Stanley receives RSNA grant

Jennifer Stanley, MD, PhD, Holman Pathway resident, has been awarded a Research Resident/Fellow Grant from Radiological Society of North America (RSNA). She will receive $30,000 to continue her work “Exploiting Radiation Induced Anti-tumor Immunity in Advanced-stage and Metastatic Ovarian Cancer”.